Estimates a null correlation matrix from data using simple z score threshold
estimate_null_correlation_simple(data, z_thresh = 2, est_cor = TRUE)a mash data object, eg as created by mash_set_data
the z score threshold below which to call an effect null
whether to estimate correlation matrix (TRUE) or the covariance matrix (FALSE).
Returns a simple estimate of the correlation matrix (or covariance matrix) among conditions under the null. Specifically, the simple estimate is the empirical correlation (or covariance) matrix of the z scores for those effects that have (absolute) z score < z_thresh in all conditions.
simdata = simple_sims(50,5,1)
data = mash_set_data(simdata$Bhat, simdata$Shat)
estimate_null_correlation_simple(data)
#> condition_1 condition_2 condition_3 condition_4 condition_5
#> condition_1 1.00000000 0.08190116 0.16592180 0.09587405 0.26978201
#> condition_2 0.08190116 1.00000000 -0.04745009 -0.14812270 0.10633083
#> condition_3 0.16592180 -0.04745009 1.00000000 0.04719117 0.23520179
#> condition_4 0.09587405 -0.14812270 0.04719117 1.00000000 -0.01296703
#> condition_5 0.26978201 0.10633083 0.23520179 -0.01296703 1.00000000