Last updated: 2023-10-03
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Knit directory: mmbr-rss-dsc_stephen/
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This is result from our mvSuSiE RSS simulation 2 traits using UKB data. There are 600 datasets. The max PVE across traits is 0.0005. There are 2 causal variants per simulated data.
For each dataset, we simulate signals with different signal correlation and residual correlations.
Signal correlation:
\(\rho\) = 0
\(\rho\) = 0.25
\(\rho\) = 0.5
\(\rho\) = 0.75
\(\rho\) = 1
mixture of effects: see Artificial Structure 2 traits section in here
Residual correlation:
V_corr = 0
V_corr = 0.4
V_corr = 0.8
For mvSuSiE, we estimate the residual correlations using the variants close to null.
With mixture effects
V_corr = 0
V_corr = 0.4
V_corr = 0.8
With mixture effects
With mixture effects
V_corr = 0
V_corr = 0.4
V_corr = 0.8
With mixture effects